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Gilead Ops in For Three Programs in Arcus Biosciences Portfolio

Aims to accelerate clinical development in oncology and facilitate the exploration of treatment combinations across portfolios.

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By: Kristin Brooks

Managing Editor, Contract Pharma

Gilead Sciences, Inc. exercised its options to three programs in Arcus Biosciences’ clinical-stage portfolio, including both anti-TIGIT molecules, domvanalimab and AB308, as well as etrumadenant and quemliclustat, with payments to Arcus totaling $725 million.   Domvanalimab is an Fc-silent anti-TIGIT antibody in Phase 2 and Phase 3 studies in non-small cell lung cancer (NSCLC) and AB308 is an Fc-enabled anti-TIGIT antibody in Phase 1. Etrumadenant is a dual adenosine A2a/A2b receptor antagonis...

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